Mechanisms of neuronal remodelling |
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ABOUT THE workshopDuring neural development, exuberant connections are first formed and later eliminated by regressive changes in neuronal morphology, which establish the mature pattern of dendrites and axons. Such neuronal remodelling is widespread across the animal kingdom, from insects to humans, and forms an essential part of nervous system wiring. As excessive or reduced neuronal remodelling might contribute to neurological diseases, remodelling is a Janus-faced process with physiological, as well as pathological roles - akin to programmed cell death. Understanding how neurites are remodeled during development should provide a broader insight into the process of axon destruction during disease and following injury. This EMBO Workshop will focus on the cellular and molecular mechanisms underlying neuronal remodelling across different animal models and their relation to the proper function of the nervous system. This EMBO Workshop is cofunded by the Israeli Science Foundation. In this EMBO Workshop, we will focus on important unresolved questions on the mechanisms of neuronal remodelling. These will include:
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Location : Kibbutz Ein-Gedi, Israel Contact : http://events.embo.org/14-neuronal-remodelling/index.html |