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Program

Overview

Program Overview

Last update 02.09.2025

AM2025 Overview

Invited Speakers

A list of all invited speakers with their details can be found on the about page.

Abstract Book & Program Book

A printed version of the Program book will be provided to all participants during the on-site registration.

Please note that to save paper the full Abstractbook with all abstracts and particpants list is only available online as PDF download for registered participants after login to the registration system shortly before the meeting.

Poster Table:

Download the Poster Table (PDF, 21.9.2025).
PosterTable mini
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Floor plan

ÖGMBT AM25 VenuePlan A4 v4 1

Wed, 24.9.

Detailed Program

Wednesday, September 24th, 2025

11:00 - 11:20

Welcome address

Moderation: Johanna Gostner (Medical University of Innsbruck, AT), Lukas A. Huber (Medical University of Innsbruck, AT), Ludger Hengst (Medical University of Innsbruck, AT)

M.EG.180/ L.EG.200
11:20 - 12:00

Plenary 1

Chair: Ludger Hengst (Medical University of Innsbruck, AT)

M.EG.180/ L.EG.200
11:20 - 12:00

Veronika Sexl (University of Innsbruck, AT)

From JAK-STAT to CDK6 A scientist`s journey through signaling in leukemia    

 
12:00 - 12:20

Science Flashes 1

Chair: Ludger Hengst (Medical University of Innsbruck, AT)

M.EG.180/ L.EG.200
 

Jackson Fontaine (Medical University of Innsbruck, AT)

Novel passive transfer mouse model of Anti-IgLON5 disease to study circuit mechanisms underlying motor dysfunction

 
 

Daniel Ramel (University of Graz, AT)

Tackling the knotweed problem by its roots, using an RNAi-based herbicide.

 
 

Dominik K. Großkinsky (AIT Austrian Institute of Technology, AT)

Exploring the role of endophytes for improving cryopreservation of potato

 
 

Jakob Prömer (Medical University of Vienna, AT)

Characterizing serine phosphorylation in Muscle Specific Kinase (MuSK)

 
 

Lena Guerrero Navarro (University of Innsbruck, AT)

TFEB orchestrates stress recovery and paves the way for senescence induction in human dermal fibroblasts

 
 

William Olson (Institute for Biomedical Aging Research, AT)

Age-associated B cell fate choice is dependent on Bach2 upregulation

 
 

Alice Cassiani (BOKU University, AT)

In depth investigation of actinobacterial coproporphyrin ferrochelatase

 
 

Natalia Regina Melo Santos (Medical University of Innsbruck, AT)

Metabolic features of cancer cells during contact guidence migration

 
 

Adam Pollio (Medical University of Innsbruck, AT)

The elucidation of TM9SF4 function in migration and polarization.

 
12:20 - 13:00

Lunch

Foyer
13:00 - 14:15

Poster Session 1

Foyer
14:15 - 15:45

S1: Neural circuits in health and disease

Chairs: Sabine Liebscher (Institute of Neurobiochemistry, AT), Johannes Passecker (Medical University of Innsbruck, AT)

M.EG.180/ L.EG.200
14:15 - 14:45

Katharina Schmack (Francis Crick Institute, GB) Katharina Schmack

Striatal neuromodulators in hallucination-like perception

 
14:45 - 15:00

Elfriede Dall (Universität Salzburg, AT)

Conformational and Functional Regulation of SET by Legumain Cleavage

 
15:00 - 15:15

Mariana Spetea (University of Innsbruck, AT)

Mu and delta opioid receptor polypharmacology as a promising strategy for effective analgesia with reduced CNS-mediated risks of tolerance and physical dependence

 
15:15 - 15:30

Alexander Wallerus (Medical University of Innsbruck, AT)

Neurokraken - a fully flexible, open-source, python-based behavior platform for circuit neuroscience research

 
15:30 - 15:45

Shenyi Jiang (Ludwig Maximilian University of Munich, DE)

Impact of distinct TDP-43 pathologies on neuronal health in vivo

 
14:15 - 15:45

S2: Environment and microbiology

Chairs: Sigrid Neuhauser (University of Innsbruck, AT), Andrea Garvetto (University of Innsbruck, AT)

L.EG.220
14:15 - 14:45

Astrid Collingro (University of Vienna, AT) Astrid Collingro

Bacterial symbionts of protists and their unexplored impact on ecosystems

 
14:45 - 15:00

Katharina Russ (University of Innsbruck, AT)

Genomic and Experimental Analysis of Bacteria Interacting with Serpula lacrymans

 
15:00 - 15:15

Alexander Eschlböck (University of Innsbruck, AT)

Regulation of 6-pentyl-α-pyrone production in Trichoderma atroviride: The role of pks1 and beyond

 
15:15 - 15:30

Nikolaus Falb (BOKU University, AT)

Knockout studies & molecular enyzmology of Coproheme decarboxylase: New insights into anaerobic heme biosynthesis

 
15:30 - 15:45

Jakob Ender (Boku University, AT)

Importance of heme biosynthesis in Porphyromonas gingivalis    

 
15:45 - 16:05

Coffee Break

Foyer
16:05 - 17:35

S3: The multifaceted world of lipids

Chairs: Andreas Koeberle (University of Graz, AT), Sabrina Sailer (Medical University of Innsbruck, AT)

M.EG.180/ L.EG.200
16:05 - 16:35

Valerie O'Donnell (Cardiff University, GB) Valerie O'Donnell

Delineating the role of lipoxygenases in innate immunity, thrombosis and wound healing

 
16:35 - 16:50

Hubert Schaller (IBMP CNRS, FR)

Distinct functions of cycloartenol-derived sterols in plants

 
16:50 - 17:05

Nicolas Vitale (INCI CNRS UPR3212, FR)

Illuminating neurosecretion: Optogenetic and click chemistry novel tools highlight the multiple roles of phosphatidic acid in neurotransmitter release.

 
17:05 - 17:20

Victoria Stefan (University Hospital of the Paracelsus Medical University Salzburg, AT)

A Ketogenic Diet boosts Neuroblastoma Immunotherapy in mice

 
17:20 - 17:35

Janik Kokot (Medical University of Innsbruck, AT)

Mathematical modeling of lipid diversity by reconstructing lipid class specific fatty acyl compositions

 
16:05 - 17:35

S4: Aging, mental health, exercise and metabolism

Chairs: Markus Mandl (JKU Medical Faculty, AT), Katharina Hüfner (Medical University of Innsbruck, AT)

L.EG.220
16:05 - 16:35

André Rendeiro (CeMM Research Center for Molecular Medicine, AT) André Rendeiro

Histological aging signatures enable tissue-specific disease prediction from blood

 
16:35 - 16:50

Johannes Burtscher (University of Innsbruck, AT)

Combining exercise and hypoxia to promote healthy brain aging – a review

 
16:50 - 17:05

Linda K. Rausch (University of Innsbruck, AT)

Going to altitude with anxious-depressive symptoms - a randomized pilot trial in individuals with and without mental disorders

 
17:05 - 17:20

Sonja Großmann (University of Innsbruck, AT)

Role of Dipeptidyl peptidase-4 in Adipose stem/progenitor cells

 
17:20 - 17:35

Elisabeth Heuböck (Johannes Kepler Universität Linz - Zentrum für medizinische Forschung, AT)

  Epicardial adipose tissue as an underestimated factor of cardiovascular diseases: Isolation and characterization of functional adipogenic stem-/progenitor cells to study pathophysiological processes in vitro  

 
17:45 - 18:20

Life Sciences Awards Austria 2025

Moderator: Michael Sauer (OMV AG, AT)

M.EG.180/ L.EG.200
BMWET Logo Office

LIFE SCIENCES AWARDS AUSTRIA 2025 

Opening words by BMWET representative (BMWET, AT)

 
Boehringer Logo RGB Dark Green 2

LIFE SCIENCES PHD AWARDS 2025 LECTURES

Life Science PhD Award Austria 2025 – Basic Science

Yannick Weyer (Medical University of Innsbruck, AT) Yannick Weyer

The Dsc ubiquitin ligase complex identifies transmembrane degrons to degrade orphaned proteins at the Golgi

 
Logo Polymun

Life Science PhD Award Austria 2025 – Applied Research

Max Josef Kellner (Helmholtz Zentrum für Infektionsforschung, DE) Max Josef Kellner

Preparing for Future Pandemics:Rapid Virus Identification in Resource-Limited Settings and Modeling Zoonotic Virus Infections in Natural Reservoir Species

 
18:20 - 19:00

Rising Star Lectures

Chair: Joachim Seipelt (Nuvonis Technologies, AT)

M.EG.180/ L.EG.200
BMWET Logo Office

Life Sciences Research Award Austria 2025 – Basic Science

Victoria Deneke (Research Institute of Molecular Pathology, AT) Victoria Deneke

A conserved fertilization complex bridges sperm and egg in vertebrates

 
BMWET Logo Office

Life Sciences Research Award Austria 2025 – Applied Research

Rémi Hocq (TU Wien, AT) Rémi Hocq

Teaching a microbe how to breathe carbon monoxide: When transposons rewire metabolism

 
BMWET Logo Office

Life Sciences Research Award Austria 2025 – Excellence & Societal Impact

Eugenia Pankevich (CeMM Research Center for Molecular Medicine, AT) Eugenia Pankevich

Systematic discovery of CRISPR-boosted CAR T cell immunotherapies

 
19:00 - 22:00

Wine & Science

Foyer

Thu, 25.9.

Thursday, September 25th, 2025

09:00 - 09:40

Plenary 2

Chair: Hesso Farhan (Medical University of Innsbruck, AT)

M.EG.180/ L.EG.200
09:00 - 09:40

Anne Simonsen (Oslo University Hospital, NO) Anne Simonsen

Regulation of mitochondrial quality control and cellular bioenergetics during hypoxia

 
09:40 - 10:25

PhD Session

Chairs: Angelika Seeber (University of Innsbruck, AT), Pablo Monfort-Lanzas (Medical University of Innsbruck, AT)

M.EG.180/ L.EG.200
09:40 - 09:55

Lea Emmy Timpen (University of Innsbruck, AT)

Impact of the E2F1-BASP1 complex on regulating MYC expression

 
09:55 - 10:10

Julia Arapovic (University of Vienna, AT)

Establishment of a transient ALFA-Tagged Uncoupling Protein 3 expression system in H9c2 cells to benchmark mitochondrial protein localization, detection, and isolation workflows

 
10:10 - 10:25

Urban Leitgeb (BOKU University, AT)

The sugar connection: N-glycosylation and dimerization in myeloperoxidase biosynthesis

 
10:25 - 10:45

Science Flashes 2

M.EG.180/ L.EG.200
 

Baris Bekdas (Medical University of Innsbruck, AT)

Orm2 at the crossroads between sterol and sphingolipid metabolism

 
 

Ilaria Dorigatti (Medical University of Innsbruck, AT)

Beyond ether lipid metabolism: PEDS1 as an orchestrator in immunology

 
 

Laura Sammarco (Medicine University of Innsbruck, AT)

Characterization of the trafficking of VIP36 and VIPL and identification of new cargos

 
 

Martina A. Höllwarth (Medical University of Innsbruck, AT)

Unveiling the subunit topology of BORC assemblies at the lysosomal membrane using crosslinking mass spectrometry

 
 

Marco Reindl (Medical University of Graz, AT)

Charged for action: precision delivery of an antimicrobial peptide via polymer-coated nanoparticles enhances efficacy

 
 

Lucia Parráková (Medical University of Innsbruck, AT)

Formaldehyde exposure alters cell cycle progression and metabolic activity in human monocytic cells

 
 

Kamila Nykiel (Medical University of Innsbruck, AT)

Engineering covalent small molecule–RNA complexes in living cells

 
 

Annkatrin Bressin (Max-Planck-Institute for Molecular Genetics, DE)

New insights into the molecular basis of ARID1B haploinsufficiency associated with the Coffin-Siris syndrome

 
 

Thomas Gabler (BOKU University, AT)

The origin of coproporphyrin III presence in acne vulgaris caused by pathogenic Cutibacterium acnes type 1 strains in human skin

 
 

Hannah Marie Cebula (St. Anna's Children's Cancer Research Institute, AT)

Investigating dose-dependent ß-catenin activity in wilms tumor

 
10:45 - 11:05

Coffee Break

Foyer
11:05 - 12:35

S5: Infection and immunity

Chairs: Guenter Weiss (Innsbruck Medical University, AT), Michaela Lackner (Medical University of Innsbruck, AT)

M.EG.180/ L.EG.200
11:05 - 11:35

Christoph Bock (CeMM & Medical University of Vienna, AT) Christoph Bock

Programmed Cells? Epigenetics and Cell Engineering for Immunity and Cancer

 
11:35 - 11:50

Yelyzaveta Miller-Michlits (Medical University of Innsbruck, AT)

High-Definition Spatial Profiling of the Skin Microenvironment in Post-COVID Small Fiber Neuropathy

 
11:50 - 12:05

Martin Hermann (Medical University of Innsbruck, AT)

Clinical relevance of circulating blood microaggregates and reactivation of Epstein-Barr virus in long-term Post-COVID patients

 
12:05 - 12:20

Lourdes Rocamora Reverte (Institute for Biomedical Aging Research, University of Innsbruck, AT)

Identification of highly suppressive human regulatory T cells in old age

 
12:20 - 12:35

Natascha Kleiter (Medical University of Innsbruck, AT)

Loss of NR2F6 reduces tissue-resident macrophages and protects from Salmonella Typhimurium infection.

 
11:05 - 12:35

S6: Mechanical aspects of cell adhesion and migration

Chairs: Francesco Baschieri (Medical University of Innsbruck, AT), Francois Tyckaert (Medical University of Innsbruck, AT)

L.EG.220
11:05 - 11:35

E. Ada Cavalcanti-Adam (University of Bayreuth, DE) E. Ada Cavalcanti-Adam

Forces in receptor-mediated cell adhesion

 
11:35 - 11:50

Pere Patón González (University of Innsbruck, AT)

Topographically driven migration of cancer cells  

 
11:50 - 12:05

Melanie Emma Groninger (Medical University of Innsbruck, AT)

Unraveling the YAP1-TGFb1 axis: a key driver of androgen receptor loss in prostate cancer-associated fibroblasts

 
12:05 - 12:20

Victoria Levario Diaz (University of Bayreuth, DE)

Spatial engineering of collagen ligand nanopatterns to study integrin-dependent migration in cancer

 
12:20 - 12:35

Maximilian Jobst (University of Vienna, AT)

Metabolic modulation and mechanotransduction in T24 bladder cancer cells

 
12:35 - 13:15

Lunch

Foyer
13:15 - 14:15

Poster Session 2

Foyer
14:15 - 15:45

S7: Organelle and membrane biology

Chairs: Oliver Schmidt (Medical University of Innsbruck, AT), Hesso Farhan (Medical University of Innsbruck, AT)

M.EG.180/ L.EG.200
14:15 - 14:45

Abdou Rachid Thiam (CNRS/ENS, FR) Abdou Rachid Thiam

Lipid storage and interorganelle communication

 
14:45 - 15:00

Luca Szabo (Medical University of Innsbruck, AT)

The role of the Retriever in polarized plasma membrane recycling

 
15:00 - 15:15

Astha Purwar (Medical University of Innsbruck, AT)

Characterizing a protective function of the ESCRT machinery at the stressed plasma membrane

 
15:15 - 15:30

Niklas Schomisch (Zellbiologie, AT)

Mechanistic dissection of the ER export of the sphingolipid biosynthesis regulator Orm2

 
15:30 - 15:45

Isabel Singer (Medical University of Innsbruck, AT)

LAMTOR1 phosphorylation orchestrates protein interactions and metabolic signalling at the lysosome

 
14:15 - 15:45
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S8: Advances in toxicology and risk assessment

Chairs: Johanna Gostner (Medical University of Innsbruck, AT), Giorgia Del Favero (University of Vienna - Faculty of Chemistry, AT)

L.EG.220
14:15 - 14:45

Philip Marx-Stölting (BfR, DE) Philip Marx-Stölting

NAMs in risk assessment – challenges and perspectives

 
14:45 - 15:00

Pablo Monfort-Lanzas (Medical University of Innsbruck, AT)

Dose-response modeling from omics data in toxicology

 
15:00 - 15:15

Janice Bergen (University of Vienna, AT)

Describing the role of shape-dependent toxicity for foodborne contaminants in a human Intestinal cell model

 
15:15 - 15:30

Sophie Strich (Medical University of Innsbruck, AT)

Unraveling AKT isoform-specific activity and drug responses using cell-based assays

 
15:30 - 15:45

Celina Ablinger (Paracelsus Medical University Salzburg, AT)

Combination of lenvatinib and antibiotics: A new strategy to overcome resistance in differentiated thyroid cancer?

 
15:45 - 16:05

Coffee Break

Foyer
16:05 - 17:35

S9: RNA in gene regulation

Chairs: Sebastian Herzog (Medical University of Innsbruck, AT), Matthias Erlacher (Medical University of Innsbruck, AT)

M.EG.180/ L.EG.200
16:05 - 16:35

Maria Hondele (University of Basel, CH) Maria Hondele

DEAD-box ATPases are global regulators of membraneless organelles

 
16:35 - 16:50

Malou Hanisch (Medical University of Innsbruck, AT)

Experimental identification of preQ1-binding RNAs in the pathogenic bacterium Listeria monocytogenes

 
16:50 - 17:05

David Klingler (New York University, US)

The interplay between RNA chemical probes and RNA binding proteins: cautionary tale or new opportunity?  

 
17:05 - 17:20

Magdalena Fickl (Medical University of Innsbruck, AT)

The impact of Nsun2-mediated 5-methylcytosine on mRNA dynamics during mESC differentiation

 
17:20 - 17:35

Anna Ploner (Institute of Organic Chemistry, AT)

The stability of RNA G-quadruplexes in the gas phase

 
16:05 - 17:35

S10: Unveiling protein and cell dynamics

Chairs: Theresia Dunzendorfer-Matt (Medical University of Innsbruck, AT), Eduard Stefan (University of innsbruck, AT)

L.EG.220
16:05 - 16:35

Verena Ruprecht (University of Innsbruck, AT) Verena Ruprecht

Organelle mechano-signalling and error correction in the early embryo

 
16:35 - 16:50

Ruth Herbst (Medical University of Vienna, AT)

Unraveling the MuSK Network: A Time-Resolved Proteomic Map of Neuromuscular Signaling  

 
16:50 - 17:05

Valentina Sladky (Medical University of Innsbruck, AT)

The AID2 system offers a potent tool for rapid, reversible, or sustained degradation of essential proteins in live mice

 
17:05 - 17:20

Alexandra Fritz (University of Innsbruck, AT)

Empowering the identification and validation of drug candidates targeting oncoproteins and E3 ligase functions

 
17:20 - 17:35

Veronika Temml (Paracelsus Medical University Salzburg, AT)

Unravelling dopamine receptor selectivity: Combining in vitro studies with molecular dynamics to gain mechanistic insights

 
17:45 - 22:00

Walking Tour & Get-together @ Nattererboden

 

Fri, 26.9.

Friday, September 26th, 2025

09:00 - 09:40

Plenary 3

Chair: Lukas A. Huber (Medical University of Innsbruck, AT)

M.EG.180/ L.EG.200
09:00 - 09:40

Georg Kustatscher (University of Edinburgh, GB) Georg Kustatscher

Protein covariation advances functional annotation of the human proteome

 
09:40 - 10:00

Science Flashes 3

Chair: Lukas A. Huber (Medical University of Innsbruck, AT)

M.EG.180/ L.EG.200
 

Aleksandra Fesiuk (Medical University of Vienna, AT)

Therapeutic targeting of thyroid hormone pathway in prostate cancer

 
 

Sofia Angelini (University of Innsbruck, AT)

Modelling Batten Disease employing iPSC-derived organoids reveals early progenitor loss and accelerated neuronal differentiation

 
 

Cristina Schöpf (Medical University of Innsbruck, Biocenter Innsbruck (CCB), AT)

The antibacterial activity and therapeutic potential of an amphibian derived peptide

 
 

Armin Oberosler (University of Innsbruck, AT)

MAA analytics Analytical considerations in the purification of mycosporine-like amino acids from marine organisms

 
 

Felix Eichin (Medical University of Innsbruck, AT)

The PIDDosome - between ploidy control and cell death

 
 

Marlene Lochner (Medical University of Innsbruck, AT)

Discovering new players in inflammatory cell death

 
 

Leonie Madersbacher (Medical University of Innsbruck, AT)

Myeloid checkpoints as targets for combination immunotherapy in ovarian cancer

 
 

Katja Rungger (Medical University of Innsbruck, AT)

The intratumoral microbiome and their effects on AHR-driven immune responses in pancreatic adenocarcinoma

 
 

Lucija Kucej (Medical University of Innsbruck, AT)

Identification of a Golgi quality control network in mammalian cells

 
 

Eva Rauch (Medical University of Innsbruck, AT)

Optimisation of an XL-MS workflow to investigate the architecture of native lysosomal LAMTOR assemblies

 
10:00 - 11:00

"Your ideas, our next move" - World Café

Moderator: Petra Buchinger (buchinger Life Science Solutions, AT)

M.EG.180/ L.EG.200
11:00 - 11:20

Coffee Break

Foyer
11:20 - 12:50

S11: Stem cells, cell cycle and cancer

Chairs: Heidelinde Jäkel (Medical University of Innsbruck, AT), Frank Edenhofer (University Innabruck, AT)

M.EG.180/ L.EG.200
11:20 - 11:50

Andreas Boland (University of Geneva, CH) Andreas Boland

Structural studies of chromosome segregation.

 
11:50 - 12:05

Alessia Schirripa (University of Veterinary Medicine Vienna, AT)

Adaptive CDK Pathways Underpinning Therapy Resistance

 
12:05 - 12:20

Omar Torres-Quesada (Medical University of Innsbruck, AT)

Novel functions of the small p27KIP1 uORF-encoded peptide

 
12:20 - 12:35

Utku Horzum (Medical University of Innsbruck, AT)

A novel ERAD-to-mTORC1 signaling axis constitutes a vulnerability of multiple myeloma cells to targeting secretory proteostasis

 
12:35 - 12:50

Amelie Schurer (University of Innsbruck, AT)

Novel stem cells from the human brain - cellular and epigenetic plasticity of eNSPCs

 
11:20 - 12:50

S12: Natural products in life science research

Chairs: Cornelia Karg (University of Innsbruck, AT), Simone Moser (University of Innsbruck, AT)

L.EG.220
11:20 - 11:50

Jonathan Lindsey (North Carolina State University, US) Jonathan Lindsey

Synthesis of phyllobilins and bacteriochlorophylls – valuable phytochemicals

 
11:50 - 12:05

Stefan Hofbauer (BOKU University, AT)

Heme biosynthesis in prokaryotes - enzyme mechanisms, interactions and more

 
12:05 - 12:20

Thomas Josef Zech (Ludwig-Maximilians-Universität, DE)

The alkaloid derivative 2-Desaza-annomontine (C81) impedes angiogenesis through inhibition of CDC2-like kinases (CLKs) and β-catenin activity.

 
12:20 - 12:35

Petra Huber-Cantonati (Paracelsus Medical University Salzburg, AT)

From Molecule to Mechanism: Understanding Benzylated Dihydrochalcones in Breast Cancer Therapy

 
12:35 - 12:50

Pamela Vrabl (University of Innsbruck, AT)

Harnessing Penicillium and Talaromyces species for scalable production of potent photoantimicrobials and photoanticancer agents

 
12:50 - 13:30

Lunch

Foyer
13:30 - 14:30

Poster Session 3

Foyer
14:00 - 14:30

Company Workshop Thermo Fisher Scientific ThermoFischer logo

L.EG.220
14:00 - 15:00

ÖGMBT General Assembly

M.EG.180/ L.EG.200
15:00 - 16:30

S13: Cell death in health and disease

Chairs: Joel Riley (Medical University of Innsbruck, AT), Verena Labi (Medical University of Innsbruck, AT)

M.EG.180/ L.EG.200
15:00 - 15:30

Katia Cosentino (UNIMORE-University of Modena and Reggio Emilia, IT) Katia Cosentino

Membrane pores in cell death at the nanoscale: assembly, structure and regulation

 
15:30 - 15:45

Leonie Weber (University of Innsbruck, AT)

The BASP1 protein interferes with WNT pathway signaling

 
15:45 - 16:00

Ahmad Salti (Johannes Kepler University Linz, AT)

Transcriptomic and functional characterization of patient-derived PRPF31- retinal organoids of retinitis pigmentosa 

 
16:00 - 16:15

Paul Petermann (Medical University of Innsbruck, AT)

The PIDDosome-p53 axis dictates cell fate after cell-cell fusion

 
16:15 - 16:30

Nadine Kinz (University of Innsbruck, AT)

The role of sub-lethal mitochondrial permeabilization in B cell mutagenesis and oncogenic transformation

 
15:00 - 16:30

S14: Machine learning and perturbation in cellular systems

Chairs: Heidi Fiegl (Medical University of Innsbruck, AT), Hubert Hackl (Medical University of Innsbruck, AT)

L.EG.220
15:00 - 15:30

Johanna Klughammer (Genecenter LMU, DE) Johanna Klughammer

Multi-modal Spatial and Single-cell Profiling of Metastatic Breast Cancer and Integrated Computational Analysis

 
15:30 - 15:45

Alexander Kirchmair (Medical University of Innsbruck, AT)

Spatial profiling of cell niches to uncover mechanisms of immune evasion in cancer

 
15:45 - 16:00

Lorenzo Merotto (Dept. of Molecular Biology / Digital Science Centre (DiSC), AT)

omnideconv: a unifying framework for single-cell-informed deconvolution of transcriptomic data

 
16:00 - 16:15

Mieke Nicolaï (Medical University of Innsbruck, AT)

Deciphering the role of the healthy tissue microenvironment in early-stage NSCLC

 
16:15 - 16:30

Bernhard Eder (University of Innsbruck, AT)

Rectangle: robust cell-type deconvolution informed by single-cell RNA sequencing data

 
16:30 - 16:50

Coffee Break & 1. Quiz drawing

Foyer
16:50 - 17:30

Plenary 4

Chair: Johanna Gostner (Medical University of Innsbruck, AT)

M.EG.180/ L.EG.200
16:50 - 17:30

Peter Murray (Max-Planck-Institute of Biochemistry, DE) Peter Murray

Immunometabolic circuits that control cell viability

 
17:30 - 18:00

Closing Ceremony, Prizes for best talks/posters & 2. Quiz Drawing

Moderators: Johanna Gostner (Medical University of Innsbruck, AT), Lukas A. Huber (Medical University of Innsbruck, AT), Ludger Hengst (Medical University of Innsbruck, AT)

M.EG.180/ L.EG.200

Veronika Sexl, Universität Innsbruck, AT

Veronika Sexl

Veronika Sexl, MD Rector, University of Innsbruck Prof. Dr. Veronika Sexl is a distinguished Austrian scientist and medical professional, with decades of expertise in pharmacology, cancer research, and translational medicine. Currently serving as the Rector of the University of Innsbruck, Dr. Sexl has a storied academic and research career, including leadership roles at the Medical University of Vienna and the Veterinary University of Vienna. Her research is internationally recognized, particularly her contributions to understanding the JAK-STAT signaling pathway, leukemia progression, and the novel regulatory role of CDK6 in tumor biology. She has supervised over 20 PhD students and published over 200 scientific papers with over 16,000 citations. As a member of the and numerous scientific boards, Dr. Sexl has helped advance hematology and oncology research globally. Her accolades include the prestigious ERC Advanced Grant, the Novartis Prize for Medicine, and membership in the Austrian Academy of Sciences and the German National Academy of Sciences “Leopoldina”.  

Katharina Schmack, Francis Crick Institute, GB

Katharina Schmack

Katharina Schmack received her medical and doctoral degrees from Charité, Berlin in 2008 and 2009, respectively. She then completed her postdoctoral training, clinical scientist fellowship and psychiatry specialization at Charité, Berlin.

In 2018, she moved to Cold Spring Harbor Laboratory, New York, for a research fellowship. In 2021, she joined the Crick Institute as a Clinical Group Leader.

Her research focuses on psychosis. Her lab investigates the neural circuits and immune processes giving rise to hallucinations and other psychotic symptoms. Using a cross-species approach, her lab studies both patients and mice with behavioural tests, computational models, and in-vivo measures and manipulations. 

Astrid Collingro, University of Vienna, AT

Astrid Collingro

Astrid Collingro is a senior scientist at the Centre for Microbiology and Environmental Systems Science at the University of Vienna. She studied microbiology at the Technical University of Munich and earned her PhD from the University of Vienna in 2004.

Astrid’s research focuses on obligate intracellular bacteria, with a particular emphasis on chlamydial symbionts of protists. She investigates the diversity and evolution within the chlamydial phylum to better understand what distinguishes symbionts of protists from human pathogens. One of her main goals is to expand the number of available isolates to further explore the wide range of chlamydiae-host interactions.

Following a research stay at the Australian Institute of Marine Science, Astrid developed a strong interest in marine hosts such as corals, sponges, and algae, and the role chlamydiae play in their microbiomes. Currently, she is examining the environmental prevalence of chlamydiae and their influence on microbial eukaryotic hosts and, by extension, on microbial communities and the ecological processes they underpin.

Valerie O'Donnell, Cardiff University, GB

Valerie O'Donnell

Valerie O’Donnell completed her PhD in Biochemistry at the University of Bristol, and post-doctoral fellowships in Switzerland and USA where she studied free radical biology and its intersection with lipid oxidation, inflammation and blood pressure regulation.   Her ongoing research focuses on applying mass spectrometry to the identification of new lipids that regulate innate immunity and inflammation, in particular families of oxidized phospholipids generated by enzymes that promote blood clotting and thrombosis.  With her colleagues, she has shown that enzymatic lipid oxidation through lipoxygenases and Lands cycle can form unique bioactive phospholipids in diverse blood cells that contribute to vascular inflammatory disease through driving clotting. She is also lead of LIPID MAPS, an ELIXIR Core Data Resource that houses the globally used LIPID MAPS Classification and Nomenclature for lipids as well as numerous informatics tools and educational resources for lipid researchers.

André Rendeiro, CeMM Research Center for Molecular Medicine, AT

André Rendeiro

I am a Principal Investigator at CeMM - the Research Center for Molecular Medicine of the Austrian Academy of Sciences and a Research Group Leader at the Ludwig Boltzmann Institute for Network Medicine at the University of Vienna, leading a research group on computational and molecular methods to study human aging and pathology.

My group develops computational methods for the analysis of spatial data (spatial transcriptomics, highly multiplexed imaging), and its integration with various modalities of molecular and clinical data of individuals along their lifespan. I am particularly interested in the organization of cells at the micro-anatomical level and understanding how this changes during the lifespan of individuals and at the onset of disease.

https://rendeiro.group/

Victoria Deneke, Research Institute of Molecular Pathology, AT

Victoria Deneke

Victoria Deneke is a Postdoctoral Researcher in the laboratory of Dr. Andrea Pauli at the Institute of Molecular Pathology (IMP Vienna). Her research program within the Pauli Group focuses on uncovering the molecular mechanisms of vertebrate fertilization, utilizing the zebrafish as her main model organism. Victoria’s postdoctoral work has been supported by an HFSP Long-Term Fellowship and an FWF ESPRIT Fellowship. 

Anne Simonsen, Oslo University Hospital, NO

Anne Simonsen

Professor Anne Simonsen leads the Autophagy research group at the Inst for Cancer Research, Oslo University Hospital, and is the co-director of the Centre of Excellence CanCell (Centre for Cancer Cell Reprogramming) at the University of Oslo, Norway. She received her PhD in 1996 and during her postdoc, she identified the FYVE domain as a specific PtdIns(3)P binding domain and EEA1 as a PtdIns(3)P and RAB5 effector protein important for endosome fusion.  She started her laboratory at the University of Oslo in 2009 where she became a full professor in 2011. The main objective of the Simonsen laboratory is to unravel the molecular mechanisms involved in selective types of autophagy and their role in normal health and disease. Specific focus areas include characterization of the role of hypoxia-induced mitophagy in cancer development and protein aggregate clearance in neurodegenerative disease. Her lab also has a continued interest in ALFY and other BEACH-domain-containing proteins. They use mammalian cell lines, various in vitro approaches, and zebrafish for their discoveries. She has authored more than 120 papers and has an H-index of 66. She is a member of the Norwegian Academy of Sciences and an elected member of EMBO.

Christoph Bock, CeMM & Medical University of Vienna, AT

Christoph Bock

Christoph Bock is a principal investigator at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, professor of medical informatics and head of the Institute of Artificial Intelligence at the Medical University of Vienna. His research combines experimental biology (high-throughput sequencing, epigenetics, CRISPR screening, bioengineering) with computational methods (bioinformatics, machine learning, artificial intelligence) – for cancer, immunology, and precision medicine. Before coming to Vienna in 2012, he was a postdoc at the Broad Institute of MIT and Harvard (2008-2011) and a PhD student at the Max Planck Institute for Informatics (2004-2008). Christoph Bock is also scientific coordinator of the Biomedical Sequencing Facility of CeMM and MedUni Vienna, member of the Human Cell Atlas Organizing Committee, fellow of the European Lab for Learning and Intelligent Systems (ELLIS), and elected board member of the Young Academy in the Austrian Academy of Sciences. He has received important research awards, including an ERC Starting Grant (2016-2021), an ERC Consolidator Grant (2021-2026), the Otto Hahn Medal of the Max Planck Society (2009), the Overton Prize of the International Society for Computational Biology (2017), and the Erwin Schrödinger Prize of the Austrian Academy of Sciences (2022).

E. Ada Cavalcanti-Adam, University of Bayreuth, DE

E. Ada Cavalcanti-Adam

E. Ada Cavalcanti-Adam is a Full Professor for Cellular Biomechanics at the University of Bayreuth. Previously, she was Group Leader at the Max Planck Institute for Medical Research in Heidelberg from 2017 until 2023.

Her interdisciplinary research integrates mechanobiology, cell-matrix interactions, and bioengineering approaches to study how physical and chemical cues at the cellular interface regulate adhesion, signaling, and force transmission. She holds an habilitation in Physical Chemistry and Cell Biology from Heidelberg University, and her academic path spans degrees and residencies in Dentistry and Orthodontics (Italy and USA), a PhD in Biosciences (Heidelberg), and international experience at institutions including the University of Pennsylvania and the Max Planck Institute for Intelligent Systems.

She is a fellow of the Max Planck School Matter to Life and associate editor at Science Advances. Her contributions have been recognized with numerous awards, including the UNESCO-L’Oréal Prize for Women in Science (2008), a Marie Curie Fellowship (2003), and multiple honors from the University of Pennsylvania and professional societies.

Abdou Rachid Thiam, CNRS/ENS, FR

Abdou Rachid Thiam

Bridging Physics and Biology to Understand Lipid and Organelle Function Trained as a physicist, I transitioned into the study of lipid and organelle biology through a multidisciplinary lens, integrating physical chemistry, cell biology, and biophysical techniques. My research focuses on developing and applying in vitro and ex vivo approaches to dissect the dynamic regulation of membrane-bound organelles. By exploring the kinetic and energetic principles that govern membrane-associated processes, my team investigates how these mechanisms shape organelle function and contribute to cellular organization and homeostasis across scales.

Philip Marx-Stölting, BfR, DE

Philip Marx-Stölting

Philip Marx-Stoelting, Dr. rer. nat., ERT, is serving at the German Federal Institute for Risk Assessment as a scientific director heading the unit ‘Testing and assessment strategies’ in the pesticides safety department and the BfR working group on endocrine disruptors. He is involved in several large research projects on NAM development including PARC, where he is leading the work-package ‘hazard assessment’. He is also involved in several expert panels on EU and international (OECD) level and chairing the 3R working group of the German Society for Toxicology (GT).

Maria Hondele, University of Basel, CH

Maria Hondele

Maria Hondele is a tenure-track assistant professor of Biochemistry at the Biozentrum, University of Basel, Switzerland since 2020. Her lab investigates cellular self-assembly processes and the formation, regulation, and function of membraneless organelles, especially those associated with RNA processing. 

Dr. Hondele studied biochemistry at the University of Regensburg and trained at the University of Massachusetts on a Fulbright scholarship. She completed her PhD in chromatin biology at EMBL Heidelberg and the University of Munich with Prof. Andreas Ladurner, and conducted her postdoctoral research in RNA and condensate biology at ETH Zurich in the laboratory of Prof. Karsten Weis. 

Verena Ruprecht, University Innsbruck, AT

Verena Ruprecht

Verena Ruprecht is Professor at the University Innsbruck (UIBK) Austria and Affiliated Group Leader at the Centre for Genomic Regulation (CRG) Barcelona, Spain. She studied biophysics and completed her doctoral work in super-resolution microscopy and cellular biophysics at the Johannes Kepler University Austria. She continued her postdoctoral work in the field of cell and developmental biology at the Institute of Science and Technology (IST) Austria. Her laboratory studies single cell and multicellular dynamics during tissue development and homeostasis, with a focus on how mechanical forces regulate cell plasticity, multicellular self-organization and tissue clearance. Work of the lab further addresses cellular morphodynamics and cell fitness in the context of cancer metastasis. Her lab uses an interdisciplinary approach that combines quantitative methods from physics and biology and bridges in vivo model systems and synthetic bottom-up in vitro assays.

Georg Kustatscher, University of Edinburgh, GB

Georg Kustatscher

Georg studied Molecular Biology at the University of Salzburg, Austria, and obtained a PhD from the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, working on epigenetics in the lab of Andreas Ladurner. From 2008 to 2020 he was a Postdoc in Juri Rappsilber’s proteomics group at the Wellcome Centre for Cell Biology in Edinburgh, UK. In 2020 he established a research group at the University of Edinburgh. The aim of his lab is to understand, from a systems biology perspective, how cells regulate protein levels and how these processes are disrupted in cancer cells. The group addresses this question by combining wet-lab proteomics and computational approaches, including machine-learning.

Andreas Boland, University of Geneva, CH

Andreas Boland

Andreas Boland is an Associate Professor at the University of Geneva. He studied Biology at the University of Jena and joined the lab of Dr. Elisa Izaurralde at the MPI in Tuebignen for his PhD work, where he discovered his passion for Structural Biology. In his PostDoc work with Dr. David Barford at the MRC-LMB in Cambridge, he used cryoEM to investigate mechanisms that control cell division. His laboratory in Geneva uses structural, biochemical and biophysical methods. During cell division, each daughter cell needs to receive an identical set of sister chromatids. Duplicated chromosomes are held together by the ring-shaped cohesin complex. Separation of chromosomes at anaphase is triggered by separase, a protease that cleaves the cohesin subunit SCC1. The Boland lab studies separase regulation. Andreas has received Young Investigator Awards from the Helmut Horten Foundation and EMBO.

Jonathan Lindsey, North Carolina State University, US

Jonathan Lindsey

Jonathan S. Lindsey (b. 1956) grew up in Indiana, did his undergraduate studies at Indiana University in Bloomington (1974–1978), and graduate and postdoctoral studies (1978–1984) at The Rockefeller University with Prof. David C. Mauzerall.  He was on the faculty at Carnegie Mellon University for 12 years before joining North Carolina State University in 1996.  His interests concern the science and creation of tetrapyrrole macrocycles (porphyrins, chlorins, bacteriochlorins) and their roles in photosynthesis-like phenomena.  A continual focus over the years has concerned synthetic methodology in the tetrapyrrole arena, which has in recent years been directed to gain access to natural members including chlorophylls and open-chain derivatives, the phyllobilins.  To advance the photosciences, he also has developed the PhotochemCAD program and spectral databases.

Katia Cosentino, UNIMORE-University of Modena and Reggio Emilia, IT

Katia Cosentino

Katia Cosentino studied Chemistry at the University of Calabria, Italy, and obtained a PhD from the same institution. During her doctoral studies, she spent time at ETH Zurich, where she developed a strong interest in biophysics and membrane biology. After completing her PhD, she joined the group of Ana Garcia-Sáez, first at the German Cancer Research Center (DKFZ) in Heidelberg, and later as a Max Planck Fellow and senior scientist at the Institute of Biochemistry in Tübingen, Germany. In 2018, she was awarded a Baden-Württemberg Elite Program grant to establish her independent research group, and in 2019 she was appointed Junior Professor of Molecular Cell Biophysics at the University of Osnabrück. Since 2025, she has been based at the University of Modena and Reggio Emilia, where she leads the Cell Death Biophysics group.

Her research combines biophysics, biochemistry, cell biology and high-resolution fluorescence microscopy to investigate the molecular mechanisms of regulated cell death. Her current work explores the function of Gasdermin proteins and their role in membrane permeabilization during pyroptotic cell death.

Johanna Klughammer, Genecenter LMU, DE

Johanna Klughammer

In my research I use high-dimensional (spatio-)molecular data in combination with computational approaches to understand how cells work together efficiently in order to form multicellular organisms and what happens if they fail to do so in the case of diseases such as cancer. I am interested in molecular (epigenome, transcriptome, proteome) as well as evolutionary aspects of this fascinating phenomenon. I completed my undergrad studies in Biomedicine at the University of Würzburg in 2012 and my PhD studies in computational epigenomics and malignant disease at CeMM and the Medical University of Vienna in 2017. After a short postdoc phase, I moved to the Broad Institute in Boston for my postdoctoral research in computational (spatio-)genomics. In September 2021 I started my own lab for Systems Immunology at the Gene Center of the LMU Munich.

Peter Murray, Max-Planck-Institute of Biochemistry, DE

Peter Murray

Peter Murray is a senior group leader at the Max-Planck-Institute for Biochemistry in Martinsried, Germany (near Munich) where he moved in 2017 after 19 years at St. Jude Children’s Research Hospital in Memphis, Tennessee. He is also an Honorary Professor in the medical faculty at the Technical University of Munich. Murray’s laboratory is focused on immune regulatory events mediated by metabolic crosstalk. He is best known for work on macrophages, IL-10 and arginine metabolism in immunity. Current research is his laboratory centers on how the immune system control ferroptosis and more specifically anti-ferroptosis through regulated amino acid metabolism. An extension of this work concerns pro-cancer effects of the immune system that suppress ferroptosis in stressed malignant cells. Further information can be found: http://www.biochem.mpg.de/murray.

 

 

Social Program

Social Program

Wine & Science 

JT22 WineScience

Sept 24, 19:00-22:00

The ÖGMBT Annual Meeting is also famous for its “Wine & Science” reception (Wednesday evening, September 24), which is included in the registration fee. This welcome reception is held within the industry exhibition area. The exhibitors bring along wine for tasting with the participants and ÖGMBT takes care of cheese and desserts. There are many wine specialties to taste and we have already counted at one of the tastings about 120 different varieties - but don't worry, there are also non-alcoholic offers ;-) Just join and enjoy the networking!

Get Together @ Nattererboden
Sept 25, 18:00-22:00Nattererboden 2023 110

Exploring the beautiful environment of Innsbruck we will take a guided walk (approx. 85 min) starting at the CCB Innsbruck. Local guides will show the groups around and share some facts about Innsbruck.

All groups will end up at the traditional restaurant “Nattererboden”. A welcome drink and flying snacks are on us. Additional culinary delights can be chosen from an event menu. The groups will walk back to the CCB with our guides and some really fancy gadgets afterwards. For those preferring to use public transportation take into account it takes 16 minutes to reach the bus stop. The last regular bus leaves at 10:00 pm. To inquire your connection kindly use this QR code IBK Oeffi QR.

Space is limited. So kindly sign in on our event list at the registration desk upon registration and choose from the elaborate menu. We are very much looking forward enjoying a lovely evening with all of you.

 

 

 

 

 

Industry Exhibition

Industry Exhibition

The industry exhibition will showcase companies and institutions presenting their products & services for the life sciences community.

Exhibitor Quiz

JT22 ExhibitorQuiz

All meeting attendees can take part in the exhibitor quiz and win prizes. Each participating exhibitor prepared a question and the correct answer can be found at their respective booth confirming. Only quiz sheets with all the correct answers and stamps from every participating booth will be taking into consideration for the lottery drawing of the prizes sponsored by the exhibitors. On Friday, Sept 26, there will be two prize drawings:

  • The first drawing of the less valuable prizes will take place during the last lunch break
  • The three winners of the main quiz prizes will be awarded during the closing ceremony

Connecting Generations

Connecting Generations – A networking game for Scientists!

ConGenCardTemplateNetworking goes next-level with Connecting Generations. This game is a unique opportunity for experienced scientists to connect with enthusiastic students, share insights and inspire the next generation organized by ÖGMBT YLSA. On the other side, students get the chance to engage with top scientists, learn from their experiences and exchange ideas. A bonus for students: they have the chance to win an exciting prize—all while making real connections.

How it works:

  • Spot the experienced scientists – Scientists who are in the game will have a coloured dot on their conference badge. That’s your signalto start a conversation!
  • Talk First, Collect Later – Each experienced scientist has a unique card with their portrait, career insights and fun answers to kick off a great discussion.
  • Here’s the catch: you have to actually talk, do not only ask for the card.
  • Build Your Collection – The more conversations you have, the more cards you’ll collect.
  • Throw your collection into the Card Box at the registration desk until Friday, Sept 26, 13:30.
  • Win big time – on the same day, 17:30- 18:00, we’ll raffle off a prize to the student with the most cards.

This is your chance to break the ice, get inspired and make (maybe) career-changing connections in a fun and informal way.

Workshop

Workshop

Hydra Bio plasma-FIB: A versatile tool for structural research across scales and temperatures

 

Company Workshop Thermo Fisher Speaker picture by Javier Fernandez Collado, Thermo Fisher Scientific

 

Sept 26, 14:00 - 14:30, Lecture room: L.EG.220

Join us for an engaging workshop on the Hydra Bio Plasma-FIB technology. This session will cover a wide range of applications, from volume electron microscopy to cryo-lamella preparation and the benefits of multi-ion species milling. Learn how Hydra Bio's advanced capabilities can enhance your research across various fields and specimen types. Don't miss this opportunity to expand your knowledge and explore the full potential of Hydra Bio Plasma-FIB in pathology, plant biology, biomaterials, structural biology, and more.

Thermo Fisher Scientific Red BG 600x400px

 

"Your ideas, our next move" - World Café

"Your ideas, our next move" - World Café

WorldcafeDuring the conference you will have the chance to share the issues and topics that matter most to you – whether well-known areas such as career development or networking, or completely new aspects and unmet needs we may not have considered yet – by writing them on our Idea Walls. Until Thursday (Sept 25) afternoon, participants can contribute their ideas openly and freely. On Thursday afternoon, the submitted ideas will be collected and clustered by the ÖGMBT team and the moderator – so that on Friday, Sept 26, 10-11 am, we can bring a clear and structured set of topics into our World Café session.

The World Café will be a guided and moderated process by Petra Buchinger (www.buchinger.org, buchinger Life Science Solutions, AT) where we discuss, explore and deepen these themes together in small groups. The aim is not to create a binding list of priorities, but to capture inspiration and identify what really moves the community. Some participants may even form self-organized groups to take ideas further, while ÖGMBT and YLSA may provide support where possible. If you would like to stay informed about the outcomes and next steps, you will also have the opportunity to sign up during the session.

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