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UID:
CATEGORIES:Workshop
SUMMARY:MASLD: From novel liver model systems to organelle pathophysiology
LOCATION:Spetses Island, Greece
DESCRIPTION;ENCODING=QUOTED-PRINTABLE:	The course at a glance\n\n	The liver plays a central role in metabolism.&n
 bsp; A disbalance in the synthesis, secretion, and uptake of lipids can cau
 se MASLD (metabolic dysfunction-associated steatotic (fatty) liver disease)
 . MASLD can lead to hepatic inflammation (MASH), fibrosis, cirrhosis, and h
 epatocellular carcinoma. The numbers are devastating: MASLD is already an e
 pidemic with a worldwide prevalence of 30% (!) and is considered the most f
 requent cause of chronic liver disease and failure. About 20% of MASLD-affe
 cted individuals have MASH and again ~20% of this group will develop liver 
 cirrhosis over the next 3-4 decades. With the increasing numbers of obesity
  worldwide, these numbers are expected to significantly rise even further. 
 Preventive measures and drug development are urgently needed. \n\n\n	I
 n the last years we have witnessed a surge of various new and promising mod
 el systems, representing key aspects of liver function and sometimes even l
 iver structure. This bears great promise for the elucidation of molecular a
 nd cellular pathways involved in MASLD, ultimately allowing the identificat
 ion of novel druggable key nodes. For this advanced course, we will bring t
 ogether experts and frontiers in five highly relevant and interconnected to
 pics to teach and discuss the basics, as well as state-of-the-art, in liver
  (patho)physiology, hepatocyte metabolism, liver fibrosis, hepatocellular c
 arcinoma, and the development of novel model systems.\n\n\n	The course is f
 or PhD students and early-career researchers, with lectures to teach and di
 scuss the basics as well as the state-of-the-art. It is organized in an inf
 ormal setting, held in the Anargyrios and Korgialenios School at the beauti
 ful island of Spetses (Greece), with many sessions and activities scheduled
  to stimulate interactions between the participants and the speakers, from 
 round table discussions and poster presentations to meet-the-expert-on-the-
 beach and diners in local restaurants with speakers in small groups.\n\n\n	
 Organizer: Bernd Helms (Utrecht University, The Netherlands)\n\n\n	 \n
CONTACT:www.masld2026.febsevents.org
DTSTAMP:20260412T004458Z
DTSTART;TZID=Europe/Vienna:20260903T100000
DTEND;TZID=Europe/Vienna:20260908T170000
SEQUENCE:1
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