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UID:
CATEGORIES:Workshop
SUMMARY:MASLD: From novel liver model systems to organelle pathophysiology
LOCATION:Spetses Island, Greece
DESCRIPTION;ENCODING=QUOTED-PRINTABLE:<h1>	The course at a glance</h1><p>	The liver plays a central role in metab
 olism.&nbsp; A disbalance in the synthesis, secretion, and uptake of lipids
  can cause MASLD (metabolic dysfunction-associated steatotic (fatty) liver 
 disease). MASLD can lead to hepatic inflammation (MASH), fibrosis, cirrhosi
 s, and hepatocellular carcinoma. The numbers are devastating: MASLD is alre
 ady an epidemic with a worldwide prevalence of 30% (!) and is considered th
 e most frequent cause of chronic liver disease and failure. About 20% of MA
 SLD-affected individuals have MASH and again ~20% of this group will develo
 p liver cirrhosis over the next 3-4 decades. With the increasing numbers of
  obesity worldwide, these numbers are expected to significantly rise even f
 urther. Preventive measures and drug development are urgently needed.&nbsp;
 </p><p>	In the last years we have witnessed a surge of various new and prom
 ising model systems, representing key aspects of liver function and sometim
 es even liver structure. This bears great promise for the elucidation of mo
 lecular and cellular pathways involved in MASLD, ultimately allowing the id
 entification of novel druggable key nodes. For this advanced course, we wil
 l bring together experts and frontiers in five highly relevant and intercon
 nected topics to teach and discuss the basics, as well as state-of-the-art,
  in liver (patho)physiology, hepatocyte metabolism, liver fibrosis, hepatoc
 ellular carcinoma, and the development of novel model systems.</p><p>	The c
 ourse is for PhD students and early-career researchers, with lectures to te
 ach and discuss the basics as well as the state-of-the-art. It is organized
  in an informal setting, held in the Anargyrios and Korgialenios School at 
 the beautiful island of Spetses (Greece), with many sessions and activities
  scheduled to stimulate interactions between the participants and the speak
 ers, from round table discussions and poster presentations to meet-the-expe
 rt-on-the-beach and diners in local restaurants with speakers in small grou
 ps.</p><p>	Organizer: Bernd Helms (Utrecht University, The Netherlands)</p>
 <p>	&nbsp;</p>
CONTACT:www.masld2026.febsevents.org
DTSTAMP:20260412T052106Z
DTSTART;TZID=Europe/Vienna:20260903T100000
DTEND;TZID=Europe/Vienna:20260908T170000
SEQUENCE:1
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