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Program

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 Program Outline :: Detailed Program

UPDATE: 21.07.21: Session descriptions, Speaker and chair biosketches updated.

Program Outline

 

Calendar Week 38

Mon. 20.9.

Opening Ceremony - live on YouTube
Bestowal of “Life Science Awards Austria ‘21”, awardee lectures

Tues. 21.9.

#1: Chromatin and gene regulation
KEYNOTE: Bas van Steensel, NL Cancer Inst. - live on YouTube

 

#2: Cell Biology and Biochemistry of Lipids

Wed. 22.9.

#3: RNA Biology

 

#4: Biophysics of Signal Transduction

Thur. 23.9.

#5: Proteostasis and membrane trafficking

 

#6: Immunology

 

 

Calendar Week 39

Tues. 28.09.

#7: Cell Division

 

#8: Toxicology

Wed. 29.09.

#9: Single-cell multiomics

 

#10: Metabolic Signaling
KEYNOTE: Lisa Henske, Harvard Medical School - live on YouTube

Thurs. 30.09.

#11: Biotech

 

 

Calendar Week 41

Tues. 12.10.

#12: Mechanisms of Neurodegeneration

Wed. 13.10.

#13: Stem Cells

 

#14: Host-Pathogen Interactions

Thurs. 14.10.

#15: Translational Oncology
KEYNOTE: Douglas Hanahan, EPFL - live on YouTube
Closing & Awards Ceremony - live on YouTube

 

Detailed Program

Please click on the respective session title to view detailed information. You can view speakers/chairs biosketch by clicking on their portrait.

Mon 20.09: Opening & Life Science Austria Award Ceremony - live on YouTube

Chairs

Lukas A. Huber

Lukas A. Huber
ÖGMBT President, Institute of Cell Biology, Medical University of Innsbruck/AT

Hesso Farhan

Hesso Farhan
Institute of Pathophysiology, Medical University of Innsbruck/AT

 
Plenary Speakers

Fleischhacker Wolfgang

W. Wolfgang Fleischhacker, MD
President of the Medical University of Innsbruck/AT

 

Tue 21.09: #1: Chromatin and gene regulation - sponsored by LabBuddy Logo

Session Description

Gene regulation is orchestrated by a fascinating ensemble of factors, ranging from transcription factor proteins to RNA and to chromatin, requiring intricate cooperation between the different players. Chromatin- and RNA-mediated mechanisms are at the heart of gene regulatory strategies, and the KEYNOTE given by Bas van Steensel as well as the two talks given by plenary speakers Andreas Ladurner and Mathias Munschauer, will provide insight into these topics. Further aspects will be covered by short talks selected from submitted abstracts.

Chairs

Alexandra Lusser

Alexandra Lusser
Institute of Molecular Biology, Medical University of Innsbruck/AT

Matthias Erlacher

Matthias Erlacher
Division of Genomics & RNomics, Medical University of Innsbruck/AT

Sebastian Herzog

Sebastian Herzog
Institute for Developmental Immunology, Medical Univ. of Innsbruck/AT

 
Plenary Speakers

Andreas Ladurner

Andreas Ladurner
Department of Physiological Chemistry, Biomedical Center LMU München/DE

Mathias Munschauer

Mathias Munschauer
HIRI Helmholtz Institute for RNA-based Infection Research, Würzburg/DE

KEYNOTE: Bas van Steensel

KEYNOTE: Bas van Steensel - live on YouTube
Netherlands Cancer Institute (NKI), Amsterdam/NL

 

Company/Special Presentations

Company Workshop 1 by CompanyLogo

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Affiliation

"Presentation Title"

Company Workshop 2 by CompanyLogo

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Affiliation

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Tue 21.09: #2: Cell Biology and Biochemistry of Lipids - sponsored by CompanyLogo

Session Description

This session will focus on all aspects of lipids ranging from emerging functions of lipid species, state-of-the-art lipid analytics, nutritional aspects of lipids to lipid metabolism in health and disease. We want to gather scientists covering fields from basic research to physicians that are united by their common interest in lipids and will discuss in this interdisciplinary session.

Chairs

Kathrin Watschinger

Katrin Watschinger
Institute of Biological Chemistry, Medical University of Innsbruck/AT

Markus Keller

Markus Keller
Institute of Human Genetics, Medical University of Innsbruck/AT

 
Plenary Speaker

Ruth Birner-Grünberger

Ruth Birner-Grünberger
Institute of Chemical Technologies and Analytics, Vienna University of Technology/AT

Lipid hydrolysis in cancer

Claypool Steven

Steven Claypool
The Johns Hopkins School of Medicine, Baltimore/US

Mitochondrial membrane musings

 

Company/Special Presentations

Company Workshop 1 by CompanyLogo

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First Name, Last Name
Affiliation

"Presentation Title"

Company Workshop 2 by CompanyLogo

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Affiliation

"Presentation Title"

 

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Wed 22.09: #3: RNA Biology - sponsored by CompanyLogo

Session Description

RNA is a versatile molecule that is not only able to store the genetic information but also performs regulatory functions as well as catalytic activities. The variability of the biological role of RNA, its chemical composition and processing, as well as its potential as catalytic tool are highlighted in the two main talks given by Stepanka Vanacova and Claudia Höbartner. Additional topics covering RNA biology will be presented in selected short talks and science flashes.

Chairs

Matthias Erlacher

Matthias Erlacher
Division of Genomics & RNomics, Medical University of Innsbruck/AT

Sebastian Herzog

Sebastian Herzog
Institute for Developmental Immunology, Medical Univ. of Innsbruck/AT

Alexandra Lusser

Alexandra Lusser
Institute of Molecular Biology, Medical University of Innsbruck/AT

 
Plenary Speakers

Claudia Höbartner

Claudia Höbartner
Institute of Organic Chemistry, Julius-Maximilians-Universität Würzburg/DE

Stepanka Vanacova

Stepanka Vanacova
CEITEC - Central European Institute of Technology, Prague/CZ

 

Company/Special Presentations

Company Workshop 1 by CompanyLogo

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Affiliation

"Presentation Title"

Company Workshop 2 by CompanyLogo

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Affiliation

"Presentation Title"

 

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Wed 22.09: #4: Biophysical and Structural Aspects of Signaling Proteins - sponsored by CompanyLogo

Chairs

Teresia Dunzendorfer

Theresia Dunzendorfer
Institute of Biological Chemistry, Medical University of Innsbruck/AT

Martin Tollinger

Martin Tollinger
Institute of Organic Chemistry, University of Innsbruck/AT

 
Plenary Speaker

Thomas Leonard

Thomas Leonard
Max Perutz Labs, University of Vienna/AT

Size matters – mechanistic insights into growth factor signaling

 

Company/Special Presentations

Company Workshop 1 by CompanyLogo

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First Name, Last Name
Affiliation

"Presentation Title"

Company Workshop 2 by CompanyLogo

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Affiliation

"Presentation Title"

 

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Thu 23.09: #5: Proteostasis and membrane trafficking - sponsored by CompanyLogo

Session Description

In this session we will focus on proteostasis within the secretory pathway and its role in diseases. We invite submissions from all scientists working on molecular, cellular and organismic aspects of proteostasis. The topics include but are not limited to quality control and trafficking in the ER, Golgi, mitochondria and endolysosomal system. Furthermore, we welcome submissions from scientists in the field of autophagy, membrane trafficking and organelle homeostasis. We aim to bring together both basic and translational researchers and engage them in an interdisciplinary discussion.

Chair

Hesso Farhan

Hesso Farhan
Institute of Pathophysiology, Medical University of Innsbruck/AT

 
Plenary Speakers

Eric Chevet

Eric Chevet
Oncogenesis, Stress & Signaling Laboratory, Université Rennes 1/FR

Elif Karagöz

Elif Karagöz
Max Perutz Labs (MFPL), University of Vienna/AT

 

Company/Special Presentations

Company Workshop 1 by CompanyLogo

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First Name, Last Name
Affiliation

"Presentation Title"

Company Workshop 2 by CompanyLogo

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Affiliation

"Presentation Title"

 

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Thu 23.09: #6: Immunology - sponsored by CompanyLogo

Session Description

We are looking forward to submissions covering immune cell development, activation, and effector functions with a particular focus on mechanisms causing human diseases.

Chairs

Verena Labi

Verena Labi
Institute for Developmental Immunology, Medical University of Innsbruck/AT

Natascha HERMANN KLEITER

Natascha Kleiter
Department for Pharmacology and Genetics, Medical University of Innsbruck/AT

 
Plenary Speakers

Matteo Iannacone

Matteo Iannacone
Dynamics of Immune Responses Unit, San Raffaele Scientific Institute, Milan/IT

Susana Minguet García

Susana Minguet García
Institut für Biologie III, University of Freiburg/DE

Rational design of innovative T cell-based immunotherapies against cancer

 

Company/Special Presentations

Company Workshop 1 by CompanyLogo

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First Name, Last Name
Affiliation

"Presentation Title"

Company Workshop 2 by CompanyLogo

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Affiliation

"Presentation Title"

 

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Tue 28.09: #7: Cell division - sponsored by CompanyLogo

Chair

Stephan Geley

Stephan Geley
Division of Molecular Pathophysiology, Medical University of Innsbruck/AT

Barisic Marin

Marin Barisic
Danish Cancer Society Research Center, Copenhagen/DK

 
Plenary Speakers

Helder Maiato

Helder Maiato
Institute for Molecular and Cell Biology, University of Porto/PT

Mechanism of kinetochore fiber maturation in mammals

Sabine Elowe

Sabine Elowe
Department of Pediatrics, Laval University, Quebec City/CA

Iva Tolic

Iva Tolic
Division of Molecular Biology, Ruđer Bošković Institute, Zagreb/HR

Mechanobiology of the mitotic spindle

 

Company/Special Presentations

Company Workshop 1 by CompanyLogo

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First Name, Last Name
Affiliation

"Presentation Title"

Company Workshop 2 by CompanyLogo

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Affiliation

"Presentation Title"

 

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Tue 28.09: #8: Toxicology - sponsored by CompanyLogo

Session Description

This session will focus on all aspects of toxicology, including multidisiplinary approaches and analytical methods to assess exposure and to investigate mechanisms of toxicity associated with chemicals related to human, animal and environmental health.

Chairs

Johanna Gostner

Johanna Gostner
Division of Medical Biochemistry, Medical University of Innsbruck/AT

Herbert Oberacher

Herbert Oberacher
Institute of Legal Medicine, Medical University of Innsbruck/AT

 
Plenary Speakers

Saskia Trump

Saskia Trump
Berlin Institute of Health, Charité, Berlin/DE

Herbert Oberacher

Herbert Oberacher
Institute of Legal Medicine, Medical University of Innsbruck/AT

Simone Moser

Simone Moser
Department of Pharmacy - Center for Drug Research, University of Munich/DE

Phyllobilins – ubiquitous natural products with pharmacologically relevant activities

 

Company/Special Presentations

Company Workshop 1 by CompanyLogo

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First Name, Last Name
Affiliation

"Presentation Title"

Company Workshop 2 by CompanyLogo

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Affiliation

"Presentation Title"

 

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Wed 29.09: #9: Single-cell multiomics - sponsored by CompanyLogo

Session Description

This year we invite submissions regarding the generation, analysis, integration, and interpretation of multiomic data generated from single cells, with a special focus on innovative technologies and computational tools.

Chairs

Francesca Finotello

Francesca Finotello
Institute of Bioinformatics, Medical University of Innsbruck/AT

Andreas Pircher

Andreas Pircher
University Hospital for Internal Medicine V, Medical University of Innsbruck/AT

 
Plenary Speakers

Christoph Bock

Christoph Bock
CeMM & Medical University of Vienna, Vienna/AT

Looking into the past and future of cells: Single-cell analysis of epigenetic cell states in immunology and cancer

Diether Lambrechts

Diether Lambrechts
Department of Human Genetics, KU Leuven/NL

 

Company/Special Presentation

Company Workshop by 10x320

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"Presentation Title"

 

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Wed 29.09: #10: Metabolic Signaling - sponsored by CompanyLogo

Session Description

This session will focus on mechanisms of nutrient sensing and signal transduction that control metabolic homeostasis during health and disease. We aim to bring together physician-scientists and basic researchers to promote interdisciplinary discussion.

Chairs

Kathrin Thedieck

Kathrin Thedieck
Institute of Biochemistry, University of Innsbruck/AT

Katrin Watschinger

Katrin Watschinger
Institute of Biological Chemistry, Medical University of Innsbruck/AT

 
Plenary Speakers

Marit Westerterp

Marit Westerterp
Department of Pediatrics, University Medical Center Groningen/NL

Christiane Opitz

Christiane Opitz
German Cancer Research Center, Heidelberg/DE

KEYNOTE: Lisa Henske

KEYNOTE: Lisa Henske - live on YouTube
Brigham and Women’s Hospital/Harvard Medical School, Cambridge/US

The Pathogenesis and Therapy of Tuberous Sclerosis Complex: New Insights  

 

Company/Special Presentations

Company Workshop 1 by CompanyLogo

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First Name, Last Name
Affiliation

"Presentation Title"

Company Workshop 2 by CompanyLogo

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Affiliation

"Presentation Title"

 

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Thu 30.09: #11: Biotech - sponsored by CompanyLogo

Chairs

Christoph Griesbeck

Christoph Griesbeck
MCI – The Entrepreneurial School, Department of Biotechnology & Food Engineering, Innsbruck/AT

Casari Georg

Georg Casari
Haplogen GmbH, on behalf of Biotech Austria/AT

 
Plenary Speaker

Josef Penninger

Josef Penninger
Life Sciences Institute, University of British Columbia/CA

 

Company/Special Presentations

Company Workshop 1 by CompanyLogo

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First Name, Last Name
Affiliation

"Presentation Title"

Company Workshop 2 by CompanyLogo

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Affiliation

"Presentation Title"

 

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Tue 12.10: #12: Mechanisms of Neurodegeneration - sponsored by CompanyLogo

Session Description

In this session we will focus on molecular, biochemical and cellular mechanisms of Neurodegeneration. We invite submission from scientists working on Parkinson’s, Alzheimer’s, ALS, Frontotemporal Dementia or a rare neurodegenerative disorder. We aim to bring together scientists working on fundamental as ell as translational aspects of neurodegeneration.

Chair

Hesso Farhan

Hesso Farhan
Institute of Pathophysiology, Medical University of Innsbruck/AT

 
Plenary Speakers

Tiago Outeiro

Tiago Outeiro
Experimental Neurodegeneration, University Medical Center Göttingen/DE

Glycation: a molecular connection between diabetes and Parkinson's disease

Nilsson Per

Per Nilsson
Division of Neurogeriatrics, Karolinska Institutet, Stockholm/SE

 

Company/Special Presentations

Company Workshop 1 by CompanyLogo

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First Name, Last Name
Affiliation

"Presentation Title"

Company Workshop 2 by CompanyLogo

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Affiliation

"Presentation Title"

 

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Wed 13.10: #13: Stem Cells - sponsored by CompanyLogo

Session Description

Stem cells emerge as an attractive model system to study the pathogenesis of complex diseases as well as therapeutic interventions. Our session will shed light on the potential of stem cells to explore the underlying mechanisms of human diseases, ranging from neurodevelopmental to neurodegenerative disorders such as Autism or Parkinson’s Disease.

Chairs

Frank Edenhofer

Frank Edenhofer
Institute of Molecular Biology, University of Innsbruck/AT

Ortner Nadine

Nadine Ortner
Department of Pharmacology and Toxicology, University of Innsbruck/AT

 
Plenary Speakers

Dimitri Krainc

Dimitri Krainc
Northwestern Medicine, Feinberg School of Medicine, Chicago/US

Novarino Gaia

Gaia Novarino
Institute for Science and Technology, Klosterneuburg/AT

 

Company/Special Presentations

Company Workshop 1 by CompanyLogo

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First Name, Last Name
Affiliation

"Presentation Title"

Company Workshop 2 by CompanyLogo

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Affiliation

"Presentation Title"

 

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Wed 13.10: #14: Host-Pathogen Interactions - sponsored by CompanyLogo

Chair

Hesso Farhan

Hesso Farhan
Institute of Pathophysiology, Medical University of Innsbruck/AT

 
Plenary Speaker

 Bernd T. Schmeck

Bernd T. Schmeck
Institute for Lung Research, University of Marburg/DE

 

Company/Special Presentations

Company Workshop 1 by CompanyLogo

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First Name, Last Name
Affiliation

"Presentation Title"

Company Workshop 2 by CompanyLogo

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Affiliation

"Presentation Title"

 

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Thu 14.10: #15: Translational Oncology - sponsored by CompanyLogo

Session Description

This session will focus on bridging the gap between basic research and potential clinical application in the field of cancer research. Many cancer-related aspects will be covered, such as the use of liquid biopsies as valuable tools for diagnosis, prognosis and prediction, as well as novel therapeutic strategies. In addition, we will cover the cellular and molecular aspects of tumor progression such as invasion, migration, the crosstalk of cancer cells with their microenvironment, as well as mechanisms of adaptive resistance to therapies and novel therapeutic concepts in cancer treatment. We invite both basic and translational researchers to submit applications for short talks or science flashes.

Chair

Heidelinde Fiegl

Heidelinde Fiegl
Department of Obstetrics and Gynaecology, Medical University of Innsbruck/AT

Zoller Heinz

Heinz Zoller
Hepatologic Lab, Medical University of Innsbruck/AT

 
Plenary Speakers

Jorge Barbazan

Jorge Barbazan
Cell migration and invasion, Institut Curie, Paris/FR

Feeling tight: Understanding how stromal compression regulates tumor mechanotransduction  

Catherine Alix-Panabiere

Catherine Alix-Panabières
Laboratory of Rare Circulating Human Cells, University Medical Center of Montpellier/FR

Liquid biopsy: from discovery to clinical application

KEYNOTE: Douglas Hannahan

KEYNOTE: Douglas Hanahan - live on YouTube
Laboratory of Translational Oncology/EPFL, Lausanne/CH

 

Company/Special Presentations

Company Workshop 1 by licor logo

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Affiliation

"Presentation Title"

Company Workshop 2 by biomedica 110x63

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"Presentation Title"

 

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Thu 14.10: Closing & Best Short Talk/Science Flash awards - live on YouTube

Chairs

Lukas A. Huber

Lukas A. Huber
ÖGMBT President, Institute of Cell Biology, Medical University of Innsbruck/AT

Hesso Farhan

Hesso Farhan
Institute of Pathophysiology, Medical University of Innsbruck/AT

 

 

Catherine Alix-Panabières, University Medical Center of Montpellier, FR

Catherine Alix-Panabières

Dr Catherine Alix-Panabières received her PhD degree in 1998 at the Institute of Virology, University Louis Pasteur, in Strasbourg in France. In 1999, she moved to Montpellier where she did a postdoctoral research at the University Medical Centre. During this last decade, Dr Alix-Panabières has focused on optimizing new techniques of enrichment, detection and characterization of viable circulating tumor cells (CTCs) in patients with solid tumors. She is the expert for the EPISPOT technology that is used to detect viable CTCs in patients with breast, prostate, colon, head & neck cancer and melanoma. This technology has been recently improved to detect functional CTCs at the single cell level (EPIDROP). Dr Catherine Alix-Panabières & Prof Pantel coined for the first time the term ‘Liquid Biopsy’in 2010 (Trends Mol Med).

In 2010, she achieved getting a permanent position at the Hospital and at the Faculty of Medicine of Montpellier (MCU-PH). As an associate professor, she became the new director of the Laboratory of Rare Human Circulating Cells (LCCRH).

In this unique platform LCCRH, they isolate, detect and characterize CTCs using combinations many technologies. She has authored or co-authored >110 scientific publications in this field during the last years and 12 book chapters, she is the inventor of three patents in the liquid biopsy field and she is part of French national projects: for ex, PANTHER (FUI project), STIC-METABREAST, TACTIK (PHRC) as well as of big European projects: CTC-SCAN (Transcan project), CANCER-ID (IMI project), PROLIPSY (Transcan project) and European Liquid Biopsy Academy (ELBA, Marie-Curie project).

It was a great honor for her to receive the Gallet et Breton Cancer Prize, the highest honor conferred by the French Academy of Medicine in November 2012 and, more recently, the 2017 AACR Awardfor the most cited scientific article in 2015 (Cayrefourcq et al. Cancer Res).

Jorge Barbazan, Institut Curie, FR

Jorge Barbazan

I am a cancer cell biologist interested in cancer cell migration and metastasis from a biophysics perspective. I did my PhD characterizing the molecular profiles of circulating tumor cells in colorectal cancer, and studying how adhesion molecules in CTCs regulate extravasation in hepatic capillaires. More recently, I moved to the tumor microenvironment field, trying to understand how cancer associated fibroblasts exert compressive forces on tumor cells during tumor progression. I use state of the art imaging techniques to visualize how migration/invasion patterns determine tumor metastasis. 

Ruth Birner-Gruenberger, TU Wien, AT

Ruth Birner-GruenbergerNo Biosketch submitted.

Christoph Bock, CeMM & Medical University of Vienna, AT

Christoph Bock

Christoph Bock is a Principal Investigator at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences and Professor of [Bio]Medical Informatics at the Medical University of Vienna. His research combines experimental biology (high-throughput sequencing, epigenetics, CRISPR screening, synthetic biology) with computational methods (bioinformatics, machine learning, artificial intelligence) – for cancer, immunology, and precision medicine. Before coming to Vienna, he was a postdoc at the Broad Institute of MIT and Harvard (2008-2011) and a PhD student at the Max Planck Institute for Informatics (2004-2008). Christoph Bock is also scientific coordinator of the Biomedical Sequencing Facility of CeMM and MedUni Vienna, informatics group leader at the Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases (LBI-RUD), coordinator of an EU Horizon 2020 project that contributes single-cell sequencing of human organoids to the Human Cell Atlas, fellow of the European Lab for Learning and Intelligent Systems (ELLIS), and elected member of the Young Academy of the Austrian Academy of Sciences. He has received important research awards, including the Otto Hahn Medal of the Max Planck Society (2009), an ERC Starting Grant (2016-2021), an ERC Consolidator Grant (2021-2026), and the Overton Prize of the International Society for Computational Biology (2017). He was included in the global list of “Highly Cited Researchers” by Clarivate Analytics (ISI Web of Science) for 2019 and 2020. He co-founded Aelian Biotechnology, a Vienna-based startup company that develops and applies single-cell methods for high-throughput biology and drug discovery.

Eric Chevet, INSERM, FR

Eric ChevetNo Biosketch submitted.

Steven Claypool, The Johns Hopkins School of Medicine, US

Steven Claypool

Steven Claypool is a product of California’s public education system having received both his BA and MA from the UCSB. Steven’s PhD thesis focused on the trafficking of the neonatal Fc Receptor in polarized epithelial cells, work that was performed under the tutelage of Dr. Richard S. Blumberg at Harvard Medical School. For his post-doctoral studies, Steven switched gears and joined the laboratory of Dr. Carla Koehler at UCLA. There, he began his investigation of mitochondrial phospholipid metabolism, work that is the foundation for the numerous studies ongoing in the CLAYPOOL lab at Hopkins. He is currently a Professor of Physiology and Genetic Medicine, and the Director of the Cellular and Molecular Physiology Graduate Program and the Mitochondrial Phospholipid Research Center.

Sabine Elowe, Centre de Recherche du CHUQ, CA

Sabine EloweNo Biosketch submitted.

W. Wolfgang Fleischhacker, Medical University of Innsbruck, AT

W. Wolfgang FleischhackerNo Biosketch submitted.

Walter Glaser, ÖGMBT, AT

Walter GlaserNo Biosketch submitted.

Elizabeth Henske, Brigham & Women`s Hospital, Harvard Medical School, US

Elizabeth Henske

Elizabeth (Lisa) Petri Henske is the Director of the Center for LAM Research and Clinical Care at Brigham and Women's Hospital.  She is Professor of Medicine at Harvard Medical School, an Associate Member of the Broad Institute of MIT and Harvard, and a practicing medical oncologist at the Dana-Farber Cancer Institute.  Dr. Henske’s laboratory discovered that lymphangioleiomyomatosis (LAM) is caused by mutations in the tuberous sclerosis complex (TSC) genes.  She also was the first to discover that the TSC1 and TSC2 proteins physically interact.  Her research laboratory is focused on the cellular, metabolic, and immunologic mechanisms underlying the pathogenesis of angiomyolipomas and LAM.  Her current interests include the role of the tumor immune microenvironment in the pathogenesis and therapy of TSC and the role of the TFEB/TFE3 transcription factors in TSC tumorigenesis.  She is a member of the American Society for Clinical Investigation and the Association of American Physicians, and serves on the Board of Directors of The LAM Foundation and the Professional Advisory Board of the Tuberous Sclerosis Alliance.  Dr. Henske has received awards for her research from the Tuberous Sclerosis Alliance, The LAM Foundation, the American Thoracic Society, and the Society for Women's Health Research (the Medtronic Prize).  This email address is being protected from spambots. You need JavaScript enabled to view it.

 

Claudia Höbartner, University of Würzburg, DE

Claudia HöbartnerNo Biosketch submitted.

Matteo Iannacone, San Raffaele Scientific Institute & University, IT

Matteo IannaconeNo Biosketch submitted.

Elif Karagöz, Max Perutz Laboratories, AT

Elif KaragözNo Biosketch submitted.

Dimitri Krainc, Northwestern University, US

Dimitri KraincNo Biosketch submitted.

Andreas Ladurner, LMU Munich, DE

Andreas Ladurner

Our research focuses on three complementary areas of chromatin plasticity. We dissect the structure and function of important chromatin remodelling enzymes using a combination of high-resolution methods, biochemistry, protein engineering, cellular and in vivo approaches, especially in the contest of PARP signaling and DNA repair. We also study the biological role and cell biology of nuclear and mitochondrial ADP-ribosylation, a post-translational modification involved in regulating chromatin structure, DNA transcription and DNA replication upon environmental stresses. We have pioneered the discovery of ADP-ribose-sensing macrodomain proteins. Finally, we complement our studies in yeast and mammalian cells by studying the role of nutrients and metabolites in gene regulation, both in mammals and in the fruit fly Drosophila melanogaster. By applying knowledge from the field of transcription and metabolism, we are dissecting how specific cellular metabolites bind and regulate transcription factors that allow organisms to adapt to nutrients.

Our approach is defined by a multidisciplinary combination of genetics, genomics, biochemistry, cell biology, biophysics, structural biology (X-ray crystallography, cryo-EM) and the use of selected model organisms. This allows us to answer fundamental biological questions in chromatin and PARP biology and to identify, dissect and translate novel paradigms of molecular recognition and biological regulation.

Thomas A. Leonard, Max Perutz Labs, AT

Thomas A. Leonard

Thomas studied Biochemistry at the University of Bristol, U.K. before obtaining a PhD in Structural Biology at the Laboratory of Molecular Biology in Cambridge. Thomas moved to the USA in 2005 as an EMBO postdoctoral fellow at the National Institutes of Health in Bethesda, MD and started his own lab as an independent investigator at the Max Perutz Labs in 2012. He is currently Deputy Head of the Center for Medical Biochemistry at the Max Perutz Labs and Curriculum Director of a new Master course in Molecular Precision Medicine, which is a joint venture of the Medical University of Vienna and the University of Vienna. Thomas’ research group is primarily focused on how signals are propagated in the cell, with a particular emphasis on how lipid second messengers are transduced into appropriate downstream responses with high fidelity and acute spatiotemporal control. This has wide implications in both human physiology and pathology, since the dysregulation of lipid-mediated signal transduction pathways is a hallmark of many human diseases, including cancer, overgrowth and metabolic disorders, and neurological pathologies.

Helder Maiato, i3S- Instituto de Investigação e Inovação em Saúde, Universidade do Porto, PT

Helder MaiatoNo Biosketch submitted.

Susana Minguet, Universtiy of Freiburg, DE

Susana MinguetNo Biosketch submitted.

Simone Moser, Ludwig-Maximilians Universität München, DE

Simone Moser

Simone Moser studied chemistry at the University of Innsbruck, Austria and received her PhD in 2009 under the supervision of Prof. Bernhard Kräutler, working on the structure elucidation of phyllobilins. She then pursued postdoctoral studies with Prof. Kai Johnsson at EPFL, Switzerland and Prof. Elizabeth M. Nolan at MIT, USA  in the fields of target identification and mode of action studies of small molecules and peptides. After one year in Analytical Development in the pharmaceutical industry (Sandoz Biopharmaceuticals, Novartis), she returned to academia and is now a group leader at the Department of Pharmacy at LMU Munich. Her research interests lie at the interface of chemistry and biology, with the focus on the bioactivities of phyllobilins.

Mathias Munschauer, Helmholtz Institute for RNA-based Infection Research, DE

Mathias Munschauer

Mathias Munschauer started working with RNA and RNA-binding proteins as an undergraduate student in the lab of Thomas Tuschl at Rockefeller University, where he later completed his master’s thesis. He then joined an international PhD exchange program jointly operated by the Max-Delbrück Center for Molecular Medicine in Berlin (working with Markus Landthaler) and at New York University (working with Christine Vogel). In the Landthaler lab, Mathias Munschauer pioneered technologies to capture the mRNA-bound proteome and display its global protein occupancy pattern on protein coding transcripts for the first time. For his postdoctoral research, he joined the lab of Eric Lander at the Broad Institute of MIT and Harvard, where he identified a novel lncRNA-dependent topoisomerase complex. He joined the Helmholtz Institute for RNA-based Infection Research (HIRI) in 2019 as head of his independent Helmholtz Young Investigator Group. In 2021, he was appointed a Junior Professor at the Faculty of Medicine at Wuerzburg University.

Per Nilsson, Karolinska Institutet, SE

Per Nilsson

I am working on finding the molecular underpinnings of Alzheimer’s disease. My background is a PhD in molecular biotechnology from Uppsala University, Sweden. I did my postdoc at RIKEN Brain Science Institute, Japan. Since 2016 I am heading a research group at Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Sweden, where I am also Vice/Acting Head of Division of Neurogeriatrics. Our research is focused on preclinical studies using animal models of Alzheimer’s in combination with clinical studies. The research is very much focused on protein homeostasis and the role of autophagy in amyloid β and tau metabolism and their links to neurodegeneration.

Gaia Novarino, Institute of Science and Technology Austria, AT

Gaia NovarinoNo Biosketch submitted.

Christiane A. Opitz, German Cancer Research Center, DKFZ, DE

Christiane A. Opitz

Christiane Opitz’s research focusses on metabolic signaling through the aryl hydrocarbon receptor (AHR). Her laboratory investigates how this pathways regulate tumor cell intrinsic malignant properties as well as anti-tumor immunity.

The AHR is a ligand-activated transcription factor that was initially discovered as the mediator of the toxic effects of xenobiotic pollutants such as dioxin. Christiane Opitz identified tryptophan (Trp) catabolites as endogenous agonists of the AHR and demonstrated that they enhance tumor cell motility and suppress anti-tumor immunity. Her work formed a basis for the development of small molecule inhibitors of the AHR and of the Trp-degrading enzymes Trp-2,3-dioxygenase (TDO2) and interleukin-4-induced 1 (IL4I1) for cancer immunotherapy. AHR target gene expression is widely used as a readout for AHR activity. However, as AHR target gene expression is cell type- and ligand-specific, analysis of a few classical AHR target genes cannot reliably detect AHR activity across different tissues. Christiane Opitz and her team have developed a transcriptional pan-tissue AHR signature, which can detect AHR activity and the biological functions of the induced target genes irrespective of tissue and ligand and they are exploring this signature for patient stratification and treatment monitoring for therapies that modulate AHR activity, which includes immunotherapies.

Tiago Outeiro, University Medical Center Goettingen, DE

Tiago Outeiro

Prof. Tiago Outeiro graduated in Biochemistry at the University of Porto and was an Erasmus student at the University of Leeds in the UK. Prof. Outeiro did his PhD thesis at the Whitehead Institute for Biomedical research – MIT. Prof. Outeiro was a Postdoctoral Research Fellow in the Department of Neurology of the Massachusetts General Hospital – Harvard Medical School and then directed the Cell and Molecular Neuroscience Unit at IMM, Lisbon, from 2007 to 2014. Currently, Prof. Outeiro is Full Professor and the Director of the Department of Experimental Neurodegeneration at the University Medical Center Goettingen, in Germany. Prof. Outeiro holds a joint Professor position at Newcastle University in the UK. 

Josef Penninger, Life Sciences Institute, CA

Josef PenningerNo Biosketch submitted.

Bernd Schmeck, Philipps-University Marburg, DE

Bernd SchmeckNo Biosketch submitted.

Iva Tolić, Ruđer Bošković Institute, HR

Iva Tolić

Iva Tolić is a Professor of Biology and Senior Research Group Leader with tenure at the Ruđer Bošković Institute in Zagreb, Croatia. She graduated in molecular biology from the University of Zagreb. Her PhD work on cell mechanics was done with Prof. Ning Wang at Harvard. Afterwards, she did a postdoc in cell biophysics with Prof. Kirstine Berg-Sørensen at the Niels Bohr Institute in Copenhagen, Denmark, and later with Prof. Francesco Pavone at LENS - European Laboratory for Non-Linear Spectroscopy, in Florence, Italy. From 2004 until 2014 she worked as a Research Group Leader at the Max Planck Institute of Molecular Cell Biology and Genetics in Dresden, Germany. In 2015, she returned to her hometown Zagreb. Her research areas are biophysics of the spindle in mitosis and meiosis, microtubules and motor proteins.

Iva is a recipient of the prestigious grants funded by the European Research Council (ERC), Consolidator and Synergy. She has been elected to EMBO membership. In 2014, she was chosen by the journal Cell as one of 40 scientists from around the world and working in diverse biological fields, "40 under 40". She received numerous awards including the Ignaz Lieben Award of the Austrian Academy of Sciences, European Biophysical Societies Association (EBSA) Young Investigators' Medal and Prize, European Life Science Award in the category Investigator of the Year, Croatian Women of Influence Award, and National Science Award of the Republic of Croatia.

Saskia Trump, Berlin Institute of Health at Charité, DE

Saskia TrumpNo Biosketch submitted.

Marit Westerterp, University Medical Center Groningen, NL

Marit WesterterpNo Biosketch submitted.

Marin Barisic, Danish Cancer Society Research Center, DK

Marin BarisicNo Biosketch submitted.

Matthias Erlacher, Medical University of Innsbruck, AT

Matthias Erlacher

At the Institute of Genomics and RNomics we are studying various aspects of RNA biology. One focus is to dissect molecular mechanisms of protein synthesis, by employing natural and non-natural modified RNAs.

Hesso Farhan, Medical University of Innsbruck, AT

Hesso FarhanNo Biosketch submitted.

Heidelinde Fiegl, Dept. of Obstetrics and Gynecology, AT

Heidelinde Fiegl

Heidelinde Fiegl is a molecular biologist and lecturer in Experimental Gynecology at the Medical University of Innsbruck (MUI), Austria. After completing her PhD studies at the Leopold-Franzens-University (LFU) in Innsbruck, she started working as a postdoctoral research fellow at the Department of Obstetrics and Gynecology at the MUI in 2001. In 2005, she moved to the University College London and in 2006 to the Tyrolean Cancer Research Institute (TKFI) in Innsbruck. During this time, she studied DNA methylation aberrations in female malignancies intensively.

In 2007, she returned to the MUI and established a research group at the Department of Obstetrics and Gynecology focusing on the role of epigenetics and translational research in breast and gynecological cancers. In 2008, she became a lecturer in experimental gynecology, since 2010, she is the head of the Laboratory for clinical biochemistry at this department and since 2014 she is Associate Professor. In the Laboratory for clinical biochemistry tumor markers are examined as part of routine analysis, DNA is extracted from cancer tissues for subsequent genetic analyses and gynecological research questions are dealt with in collaboration with clinicians.

Beside her lecturing activities at the MUI, her scientific work now focuses on identifying biomarkers to facilitate risk prediction and individualization of cancer treatment in female malignancies. She is a member of the Austrian biobank network BBMRI.AT (Biobanking and BioMolecular resources Research Infrastructure Austria) and is involved in harmonizing quality management in biobanking. She has authored of over 90 scientific publications in international journals and books.

Francesca Finotello, Medical University of Innsbruck, AT

Francesca Finotello

Francesca Finotello earned her PhD in Bioengineering in 2014 at the University of Padova, Italy. She has longstanding expertise in multi-omics data analysis, and she is interested in the development of new computational biology methods to advance cancer immunology and precision medicine. At present, she is a postdoctoral researcher and principal investigator in the Institute of Bioinformatics of the Medical University of Innsbruck, Austria. She performs integrative analyses of bulk and single-cell multi-omics using bioinformatics and systems biology methodologies. By characterizing the landscape of cancer neoantigens, the composition of the tumor immune contexture, and the intricate multi-cellular crosstalk governing tumor-immune-stromal cell interactions in the tumor microenvironment, she aims at extracting mechanistic rationale to improve cancer immunotherapy.

Stephan Geley, Innsbruck Medical University, AT

Stephan GeleyNo Biosketch submitted.

Walter Glaser, ÖGMBT, AT

Walter GlaserNo Biosketch submitted.

Johanna Gostner, Medical University of Innsbruck, AT

Johanna GostnerNo Biosketch submitted.

Christoph Griesbeck, MCI-The Entrepreneurial School, AT

Christoph GriesbeckNo Biosketch submitted.

Sebastian Herzog, Medical University Innsbruck, AT

Sebastian Herzog

I have studied Biology at the University of Freiburg and have been trained as a Molecular Immunologist at the Max-Planck-Institute of Immunobiology under guidance of Michael Reth and Hassan Jumaa, mainly focusing on lymphocyte development and signaling. In my postdoctoral studies, I have extended my research focus to the role of non-coding RNAs, in particular microRNAs, in the immune system. Since 2013, I work as a Group Leader in the Institute of Developmental Immunology in Innsbruck. My team is still interested how microRNAs impact on the immune system both under physiological conditions as well as in oncogenic settings. However, we also try to understand how microRNAs themselves are controlled, e.g. during their biogenesis, to fulfill their role as an additional layer of precise gene regulation.

Natascha Kleiter, Medical University Innsbruck, AT

Natascha Kleiter

Natascha Kleiter (Hermann-Kleiter) is Associate Professor at the Medical University in Innsbruck, Austria, with extensive expertise in T cell biology. Her main focus is to reveal T cell-intrinsic mechanisms involved in the loss of tolerance during autoimmune or anti-cancer responses. Her recent work involved functional analysis of the nuclear orphan receptor NR2F6 in CD4 T cells during follicular T helper cell differentiation and CD8 memory formation following bacterial infection. Her research involves in vivo mouse models resembling human diseases combined with molecular and cellular technologies to identify underlying mechanisms.

Verena Labi, Medical University of Innsbruck, AT

Verena LabiNo Biosketch submitted.

Alexandra Lusser, Medical University of Innsbruck, AT

Alexandra LusserNo Biosketch submitted.

Herbert Oberacher, Medical University of Innsbruck, AT

Herbert Oberacher

Herbert Oberacher is an analytical chemist. In 2002 he received his PhD at the University of Innsbruck, Austria. After spending a year as postdoctoral fellow at the University of the Saarland, Germany, he got a position as senior researcher at the Institute of Legal Medicine of the Innsbruck Medical University, Austria. In 2007 he received the “venia docendi” for bioanalysis, and in 2011 he was appointed as Associate Professor. His research focuses on the development of new and advanced techniques for the analysis of bioorganic molecules with special emphasis on small molecules and nucleic acids. Typical fields of application include medical, biological, pharmaceutical, and environmental research. For this research, he received several awards. He has (co-)authored more than 120 publications in international scientific journals and holds three patents.

Nadine J. Ortner, University of Innsbruck, AT

Nadine J. Ortner

I have studied Molecular Biology with special focus on Neurosciences at the University of Vienna (Diploma Program, 2006-2012) and Pharmaceutical Sciences at the University of Innsbruck (PhD Program, 2012-2017). During my PhD I focused on the pharmacology of brain L-type calcium channels (with special focus on subtype-selective inhibitors) and their implication for the treatment of brain diseases such as Parkinson’s disease and Autism Spectrum Disorder. Currently I am characterizing and validating a novel Cav1.3 channelopathy mouse model of neurodevelopmental disorders.

Combining my expertise in neurobiology and pharmacology, I aim at deciphering the role of voltage-gated calcium channels in brain disorders and their pharmacological modulation as a potential therapeutic intervention. For my studies I employ molecular (cloning, generation of stable cell lines), electrophysiological (heterologous expression systems & brain slices), immunohistochemical and pharmacological methods.

Andreas Pircher, Medical University Innsbruck, AT

Andreas PircherNo Biosketch submitted.

Kathrin Thedieck, University of Innsbruck, AT

Kathrin Thedieck

Kathrin Thedieck is Professor and Institute Head of Biochemistry at the University of Innsbruck, Austria. Her research spans the field of metabolic signaling with a focus on networks converging on the metabolic master regulator mechanistic target of rapamycin (mTOR) and phosphoinositide-3 kinases (PI3Ks). Her group pioneers crosstalk of PI3K-mTOR with RNA-protein networks, and systems studies of mTOR network topology as well as its responses to metabolism and therapy. She coordinates and partners European and national consortia that develop systems approaches for precision medicine in cancer and in congenital diseases. Are you curious about Kathrin Thedieck’s research? Find out more on www.metabolic-signaling.eu

Martin Tollinger, University of Innsbruck, AT

Martin TollingerNo Biosketch submitted.

Katrin Watschinger, Medical University of Innsbruck, AT

Katrin Watschinger

After my studies of chemistry at the Innsbruck University and my PhD on neuronal calcium channels I continued my scientific curriculum at the Medical University of Innsbruck in the field of ether lipids, In 2010, I discovered the genetic identity of alkylglycerol monooxygenase (AGMO). With an Erwin-Schrödinger fellowship from the FWF I spent 12 months at the University of Oxford where I was able to launch the generation of the so far only Agmo knockout mouse which is now established in my lab. Recently, we could identify also the gene coding for plasmanylethanolamine desaturase (PEDS1), another orphan enzyme in ether lipid metabolism. This finding now allows us to dissect the roles of different types of ether lipids, the plasmalogens and plasmanyl lipids, in physiology and pathophysiology.

Heinz Zoller, Medical University of Innsbruck, AT

Heinz ZollerNo Biosketch submitted.

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