Center of Pathobiochemistry and Genetics is committed to leading edge
science and patient cytogenetic, molecular cytogenetic and molecular
genetic diagnostics. The Center’s scientific interest is stem cell research,
tumor biology, aging, reproductive genetics, lipid metabolism, and
genetic diseases.

About the research project
A funded two-year postdoctoral position, is available in the research division of Herbert Stangl (institute head) in conjunction with the group of Selma Osmanagic-Myers closely working with head of the research center Markus Hengstschläger. Our research division has a long standing interest in studying molecular mechanism particularly
related to aberrant LDL/HDL trafficking and aging that contribute to the development of liver diseases. For detailed information please check: https://www.meduniwien.ac.at/hp/en/center-for-pathobiochemistry-and-
genetics/science/institute-of-medical-chemistry-and-pathobiochemistry/

In this project we plan to use iPSC cultures with an aim to establish human liver organoids. The function of liver organoids will be characterized by cellular composition assays and functional assays. Using CRISPR/Cas9
technology in combination with patient derived iPSCs in liver organoids we aim to tackle molecular mechanisms of liver disease under physiological conditions.

The ideal candidate should have:
academic qualifications at PhD level within one or more of the following areas: molecular biology, genetics or
similar areas and documented scientific publications. Practical experience working with human pluripotent stem cells, hepatocyte differentiation, FACS analysis and CRISPR/Cas9 technology would be highly preferable. In your daily work routine you should be able to work independently but also as part of the guided team.

Apply now
Send a curriculum vitae indicating current and future research interests, previous educational and laboratory
experience including contact details for two references to bewerbungen@meduniwien.ac.at, Kennzahl: 3304/21 till 26. May 2021. The position is available for 2 years with possibility of extension.