Redox homeostasis is a prerequisite for human health, in which the p hysiological levels of nonradical reactive oxygen species function as the p rimary second messengers to modulate physiological redox signaling by orche strating multiple redox sensors. However, redox dysregulation leads to biom olecule damage and subsequent occurrence of various diseases such as cardio vascular pathology, cancer and neurodegeneration.
This FEBS Adva nced Lecture Course aims to tackle the intricate redox signaling network th at has evolved around cellular metabolism, generation of radical species, a nd cellular responses that affect growth and death. The speakers will discu ss different aspects of redox signaling involved in both physiological and pathological conditions and how dysfunction of this complex signaling netwo rk can be targeted to prevent/slow disease onset and progression. Further, different model systems as well as methodological approaches, including tra nscriptomics, metabolomics, and proteomics, will be discussed to provide st udents a wider perspective of questions, models, and approaches that can be developed for future studies.
The program offers a diverse arra y of activities, including training lectures, poster sessions, short presen tations by all participants, and “meet the expert” sessions tha t provide young scientists with the opportunity to engage directly with lea ding international experts in redox biology.
The course will tar get early-career researchers (ECRs) from different areas of basic biologica l sciences and medicine, primarily experienced PhD students and post-doctor al level scientists within 5 years after completion of their doctorate. ECR s will be selected primarily based on their qualifications relevant to the course content, their potential to contribute to the breadth of science, an d the benefit they are likely to obtain for their future careers, while ens uring a broad participation from different FEBS constituent countries and a focus on equality and diversity.
Image: neurons stained with DCF, for ROS assay; from lab of M. Perluigi.
Th e course website is under construction. Please monitor the Advanced Courses calendar for when the link becomes available.
Locati on: Spetses Island, Greece
Organizers: M arzia Perluigi, Fabio Di Domenico, Niki Chondrogianni
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CONTACT:www.febs.org/event/redox-signaling-in-the-physiopathology-of-the-human-body/?utm_medium=email&utm_campaign=January 2026 DTSTAMP:20260829T023834Z DTSTART;TZID=Europe/Vienna:20260928T100000 DTEND;TZID=Europe/Vienna:20261004T170000 SEQUENCE:1 TRANSP:OPAQUE END:VEVENT END:VCALENDAR