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UID:
CATEGORIES:Workshop
SUMMARY:ÖGMBT SEMINAR, Zweigstelle SÜD: Engineering microbes to create and harness newer-to-nature building blocks
LOCATION:HS E (NT01088), Kopernikusgasse 24, 1. OG, TUGraz, 2010 Graz
DESCRIPTION;ENCODING=QUOTED-PRINTABLE: Österreichische Gesellschaft für Molekulare
Biowissenschaften und Biotechnologie (ÖGMBT)
Austrian Ass
ociation of Molecular Life Sciences and Biotechnology
&n
bsp;
ÖGM
BT SEMINAR, Zweigstelle SÜD
Title: Engine
ering microbes to create and harness newer-to-nature building blocks <
/strong>
Invited speaker: Prof. Aditya K
unjapur, University of Delaware
Abstract:
Newer-to-nature building blocks such as non-st
andard amino acids (nsAA) can expand the repertoire
of chemistr
ies and functions that living systems can produce. However, reliance on che
mical
synthesis of nsAAs introduces several kinds of constraint
s that impact the costs and contexts where
nsAAs can be used. I
n this talk, I will describe how biosynthesis of nsAAs can create new capab
ilities
and safeguards for microbial engineering, including app
lications towards live vaccines or controlled
release of microb
es into the environment. I will also describe how one-pot semi-synthesis an
d
incorporation of nsAAs within proteins can be an attractive a
lternative for industrial maturation of
genetic code expansion
(GCE) technologies in biomanufacturing, including a route for synthesis of&
nbsp;
encodable L-phenylalanine derivatives that we have developed in
in cell-free and cellular formats.
Overall, these research dir
ections at the interface of metabolic engineering and chemical biology lay&
nbsp;
the groundwork for accelerating industrial adoption of, and unl
ocking new opportunities for, GCE for
the benefit of human and
planetary health.
Date: 12th
November 2025 at 11:00
Location: HS E (NT010
88), Kopernikusgasse 24, 1. OG, TUGraz, 2010 Graz
Contact person: Dr. Margit WINKLER This e
mail address is being protected from spambots. You need JavaScript enabled
to view it.
CONTACT:This email address is being protected from spambots. You need JavaScript enabled to view it.
//
DTSTAMP:20260612T123736Z
DTSTART;TZID=Europe/Vienna:20251111T110000
DTEND;TZID=Europe/Vienna:20251111T190000
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